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APP transgenic modeling of Alzheimer’s disease: mechanisms of neurodegeneration and aberrant neurogenesis

Neurodegenerative disorders of the aging population affect over 5 million people in the US and Europe alone. The common feature is the progressive accumulation of misfolded proteins with the formation of toxic oligomers. Alzheimer’s disease (AD) is characterized by cognitive impairment, progressive...

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Autors principals: Crews, Leslie, Rockenstein, Edward, Masliah, Eliezer
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847155/
https://ncbi.nlm.nih.gov/pubmed/20091183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00429-009-0232-6
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