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APP transgenic modeling of Alzheimer’s disease: mechanisms of neurodegeneration and aberrant neurogenesis

Neurodegenerative disorders of the aging population affect over 5 million people in the US and Europe alone. The common feature is the progressive accumulation of misfolded proteins with the formation of toxic oligomers. Alzheimer’s disease (AD) is characterized by cognitive impairment, progressive...

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Bibliografische gegevens
Hoofdauteurs: Crews, Leslie, Rockenstein, Edward, Masliah, Eliezer
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer-Verlag 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847155/
https://ncbi.nlm.nih.gov/pubmed/20091183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00429-009-0232-6
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