Modulation of aberrant CDK5 signaling rescues impaired neurogenesis in models of Alzheimer's disease

Recent studies show that in Alzheimer's disease (AD), alterations in neurogenesis contribute to the neurodegenerative process. Neurodegeneration in AD has been associated with aberrant signaling through the cyclin-dependent kinase-5 (CDK5) pathway via its activators p35/p25; however, the role o...

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Detalhes bibliográficos
Main Authors: Crews, L, Patrick, C, Adame, A, Rockenstein, E, Masliah, E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101702/
https://ncbi.nlm.nih.gov/pubmed/21368891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.2
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