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Modulation of aberrant CDK5 signaling rescues impaired neurogenesis in models of Alzheimer's disease
Recent studies show that in Alzheimer's disease (AD), alterations in neurogenesis contribute to the neurodegenerative process. Neurodegeneration in AD has been associated with aberrant signaling through the cyclin-dependent kinase-5 (CDK5) pathway via its activators p35/p25; however, the role o...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3101702/ https://ncbi.nlm.nih.gov/pubmed/21368891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.2 |
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