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Increased CDK5 Expression in HIV Encephalitis Contributes to Neurodegeneration via Tau Phosphorylation and Is Reversed with Roscovitine

Recent treatments with highly active antiretroviral therapy (HAART) regimens have been shown to improve general clinical status in patients with human immunodeficiency virus (HIV) infection; however, the prevalence of cognitive alterations and neurodegeneration has remained the same or has increased...

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書誌詳細
主要な著者: Patrick, Christina, Crews, Leslie, Desplats, Paula, Dumaop, Wilmar, Rockenstein, Edward, Achim, Cristian L., Everall, Ian P., Masliah, Eliezer
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Investigative Pathology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078446/
https://ncbi.nlm.nih.gov/pubmed/21435449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.12.033
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