Phosphorylation of collapsin response mediator protein-2 disrupts neuronal maturation in a model of adult neurogenesis: Implications for neurodegenerative disorders

BACKGROUND: Recent studies suggest that the pathogenic process in neurodegenerative disorders may disrupt mature neuronal circuitries and neurogenesis in the adult brain. Abnormal activation of CDK5 is associated with neurodegenerative disorders, and recently a critical role for CDK5 in adult neurog...

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Autori principali: Crews, Leslie, Ruf, Rebecca, Patrick, Christina, Dumaop, Wilmar, Trejo-Morales, Margarita, Achim, Cristian L, Rockenstein, Edward, Masliah, Eliezer
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204248/
https://ncbi.nlm.nih.gov/pubmed/21943307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-67
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