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Molecular mechanisms of neurodegeneration in Alzheimer's disease

Alzheimer's disease (AD) is characterized by cognitive impairment, progressive neurodegeneration and formation of amyloid-β (Aβ)-containing plaques and neurofibrillary tangles composed of hyperphosphorylated tau. The neurodegenerative process in AD is initially characterized by synaptic damage...

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Detalhes bibliográficos
Main Authors: Crews, Leslie, Masliah, Eliezer
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875049/
https://ncbi.nlm.nih.gov/pubmed/20413653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq160
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