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Kynurenines, neurodegeneration and Alzheimer’s disease

Alzheimer’s disease (AD) is one of the major causes of dementia. The pathogenesis of the disease is not entirely understood, but the amyloid β peptide (Aβ) and the formation of senile plaques seem to play pivotal roles. Oligomerization of the Aβ is thought to trigger a cascade of events, including o...

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Autors principals: Kincses, Zsigmond Tamas, Toldi, József, Vécsei, László
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822995/
https://ncbi.nlm.nih.gov/pubmed/20629991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2010.01123.x
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