Increased CDK5 Expression in HIV Encephalitis Contributes to Neurodegeneration via Tau Phosphorylation and Is Reversed with Roscovitine

Recent treatments with highly active antiretroviral therapy (HAART) regimens have been shown to improve general clinical status in patients with human immunodeficiency virus (HIV) infection; however, the prevalence of cognitive alterations and neurodegeneration has remained the same or has increased...

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Detalhes bibliográficos
Main Authors: Patrick, Christina, Crews, Leslie, Desplats, Paula, Dumaop, Wilmar, Rockenstein, Edward, Achim, Cristian L., Everall, Ian P., Masliah, Eliezer
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078446/
https://ncbi.nlm.nih.gov/pubmed/21435449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.12.033
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