Impaired neurogenesis by HIV-1-Gp120 is rescued by genetic deletion of fatty acid amide hydrolase enzyme

BACKGROUND AND PURPOSE: The HIV-envelope glycoprotein Gp120 is involved in neuronal injury and is associated with neuro-AIDS pathogenesis in the brain. Endocannabinoids are important lipid ligands in the CNS regulating neural functions, and their degeneration is controlled by hydrolysing enzymes suc...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Avraham, H K, Jiang, S, Fu, Y, Rockenstein, E, Makriyannis, A, Wood, J, Wang, L, Masliah, E, Avraham, S
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594266/
https://ncbi.nlm.nih.gov/pubmed/24571443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12657
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