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Sulfonyl Fluoride Inhibitors of Fatty Acid Amide Hydrolase
Sulfonyl fluorides are known to inhibit esterases. Early work from our laboratory has identified hexadecyl sulfonylfluoride (AM374) as a potent in vitro and in vivo inhibitor of fatty acid amide hydrolase (FAAH). We now report on later generation sulfonyl fluoride analogs that exhibit potent and sel...
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| Main Authors: | , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3678964/ https://ncbi.nlm.nih.gov/pubmed/23083016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm301205j |
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