Sulfonyl Fluoride Inhibitors of Fatty Acid Amide Hydrolase

Sulfonyl fluorides are known to inhibit esterases. Early work from our laboratory has identified hexadecyl sulfonylfluoride (AM374) as a potent in vitro and in vivo inhibitor of fatty acid amide hydrolase (FAAH). We now report on later generation sulfonyl fluoride analogs that exhibit potent and sel...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Alapafuja, Shakiru O., Nikas, Spyros P., Bharatan, Indu, Shukla, Vidyanand G., Nasr, Mahmoud L., Bowman, Anna L., Zvonok, Nikolai, Li, Jing, Shi, Xiaomeng, Engen, John R., Makriyannis, Alexandros
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2012
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678964/
https://ncbi.nlm.nih.gov/pubmed/23083016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm301205j
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