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Inhibition of fatty acid amide hydrolase activates Nrf2 signalling and induces heme oxygenase 1 transcription in breast cancer cells

BACKGROUND AND PURPOSE: Endocannabinoids such as anandamide (AEA) are important lipid ligands regulating cell proliferation, differentiation and apoptosis. Their levels are regulated by hydrolase enzymes, the fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MGL). Here, we investigated...

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Detaylı Bibliyografya
Asıl Yazarlar: Li, H, Wood, J T, Whitten, K M, Vadivel, S K, Seng, S, Makriyannis, A, Avraham, H K
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Publishing Ltd 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791989/
https://ncbi.nlm.nih.gov/pubmed/23347118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12111
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