The cannabinoid CB(2) receptor agonist AM1241 enhances neurogenesis in GFAP/Gp120 transgenic mice displaying deficits in neurogenesis

Background and Purpose: HIV-1 glycoprotein Gp120 induces apoptosis in rodent and human neurons in vitro and in vivo. HIV-1/Gp120 is involved in the pathogenesis of HIV-associated dementia (HAD) and inhibits proliferation of adult neural progenitor cells (NPCs) in glial fibrillary acidic protein (GFA...

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Detalhes bibliográficos
Main Authors: Avraham, Hava Karsenty, Jiang, Shuxian, Fu, Yigong, Rockenstein, Edward, Makriyannis, Alexandros, Zvonok, Alexander, Masliah, Eliezer, Avraham, Shalom
Formato: Artigo
Idioma:Inglês
Publicado em: The British Pharmacological Society 2014
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904265/
https://ncbi.nlm.nih.gov/pubmed/24148086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12478
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