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APP transgenic modeling of Alzheimer’s disease: mechanisms of neurodegeneration and aberrant neurogenesis

Neurodegenerative disorders of the aging population affect over 5 million people in the US and Europe alone. The common feature is the progressive accumulation of misfolded proteins with the formation of toxic oligomers. Alzheimer’s disease (AD) is characterized by cognitive impairment, progressive...

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Autori principali: Crews, Leslie, Rockenstein, Edward, Masliah, Eliezer
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer-Verlag 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847155/
https://ncbi.nlm.nih.gov/pubmed/20091183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00429-009-0232-6
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