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Inclusion formation and neuronal cell death through neuron-to-neuron transmission of α-synuclein

Neuronal accumulation of α-synuclein and Lewy body formation are characteristic to many neurodegenerative diseases, including Parkinson's disease (PD). This Lewy pathology appears to spread throughout the brain as the disease progresses. Furthermore, recent studies showed the occurrence of Lewy...

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Detalhes bibliográficos
Main Authors: Desplats, Paula, Lee, He-Jin, Bae, Eun-Jin, Patrick, Christina, Rockenstein, Edward, Crews, Leslie, Spencer, Brian, Masliah, Eliezer, Lee, Seung-Jae
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722313/
https://ncbi.nlm.nih.gov/pubmed/19651612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903691106
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