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α-Synuclein interferes with the ESCRT-III complex contributing to the pathogenesis of Lewy body disease
α-Synuclein (α-syn) has been implicated in neurological disorders with parkinsonism, including Parkinson's disease and Dementia with Lewy body. Recent studies have shown α-syn oligomers released from neurons can propagate from cell-to-cell in a prion-like fashion exacerbating neurodegeneration....
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| Publicado no: | Hum Mol Genet |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4764192/ https://ncbi.nlm.nih.gov/pubmed/26740557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv633 |
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