The role of animal models in advancing amyloid-beta immunotherapy to the clinic

Por Games, Dora, Seubert, Peter
Publicado em 2010

Increased T Cell Recruitment to the CNS after Amyloid β(1–42) Immunization in Alzheimer's Mice Overproducing Transforming Growth Factor-β1

Por Buckwalter, Marion S., Coleman, Bronwen S., Buttini, Manuel, Barbour, Robin, Schenk, Dale, Games, Dora, Seubert, Peter, Wyss-Coray, Tony
Publicado em 2006

Accumulation of Amyloid β-Protein in the Low-Density Membrane Domain Accurately Reflects the Extent of β-Amyloid Deposition in the Brain

Por Oshima, Noriko, Morishima-Kawashima, Maho, Yamaguchi, Haruyasu, Yoshimura, Masahiro, Sugihara, Shiro, Khan, Karen, Games, Dora, Schenk, Dale, Ihara, Yasuo
Publicado em 2001

Faster forgetting contributes to impaired spatial memory in the PDAPP mouse: Deficit in memory retrieval associated with increased sensitivity to interference?

Por Daumas, Stephanie, Sandin, Johan, Chen, Karen S., Kobayashi, Dione, Tulloch, Jane, Martin, Stephen J., Games, Dora, Morris, Richard G.M.
Publicado em 2008

Morphological Characterization of Thioflavin-S-Positive Amyloid Plaques in Transgenic Alzheimer Mice and Effect of Passive Aβ Immunotherapy on Their Clearance

Por Bussière, Thierry, Bard, Frédérique, Barbour, Robin, Grajeda, Henry, Guido, Terry, Khan, Karen, Schenk, Dale, Games, Dora, Seubert, Peter, Buttini, Manuel
Publicado em 2004

Amyloid deposition in the hippocampus and entorhinal cortex: Quantitative analysis of a transgenic mouse model

Por Reilly, John F., Games, Dora, Rydel, Russell E., Freedman, Stephen, Schenk, Dale, Young, Warren G., Morrison, John H., Bloom, Floyd E.
Publicado em 2003

Dentate gyrus volume is reduced before onset of plaque formation in PDAPP mice: A magnetic resonance microscopy and stereologic analysis

Por Redwine, Jeffrey M., Kosofsky, Barry, Jacobs, Russell E., Games, Dora, Reilly, John F., Morrison, John H., Young, Warren G., Bloom, Floyd E.
Publicado em 2003

Selective vulnerability of dentate granule cells prior to amyloid deposition in PDAPP mice: Digital morphometric analyses

Por Wu, Chi-Cheng, Chawla, Faisal, Games, Dora, Rydel, Russell E., Freedman, Stephen, Schenk, Dale, Young, Warren G., Morrison, John H., Bloom, Floyd E.
Publicado em 2004

Appearance of Sodium Dodecyl Sulfate-Stable Amyloid β-Protein (Aβ) Dimer in the Cortex During Aging

Por Enya, Miho, Morishima-Kawashima, Maho, Yoshimura, Masahiro, Shinkai, Yasuhisa, Kusui, Kaoru, Khan, Karen, Games, Dora, Schenk, Dale, Sugihara, Shiro, Yamaguchi, Haruyasu, Ihara, Yasuo
Publicado em 1999

Axonopathy in an α-Synuclein Transgenic Model of Lewy Body Disease Is Associated with Extensive Accumulation of C-Terminal–Truncated α-Synuclein

Por Games, Dora, Seubert, Peter, Rockenstein, Edward, Patrick, Christina, Trejo, Margarita, Ubhi, Kiren, Ettle, Benjamin, Ghassemiam, Majid, Barbour, Robin, Schenk, Dale, Nuber, Silke, Masliah, Eliezer
Publicado em 2013

Anti-α-synuclein immunotherapy reduces α-synuclein propagation in the axon and degeneration in a combined viral vector and transgenic model of synucleinopathy

Por Spencer, Brian, Valera, Elvira, Rockenstein, Edward, Overk, Cassia, Mante, Michael, Adame, Anthony, Zago, Wagner, Seubert, Peter, Barbour, Robin, Schenk, Dale, Games, Dora, Rissman, Robert A., Masliah, Eliezer
Publicado no Acta Neuropathol Commun (2017)

Reducing C-Terminal-Truncated Alpha-Synuclein by Immunotherapy Attenuates Neurodegeneration and Propagation in Parkinson's Disease-Like Models

Por Games, Dora, Valera, Elvira, Spencer, Brian, Rockenstein, Edward, Mante, Michael, Adame, Anthony, Patrick, Christina, Ubhi, Kiren, Nuber, Silke, Sacayon, Patricia, Zago, Wagner, Seubert, Peter, Barbour, Robin, Schenk, Dale, Masliah, Eliezer
Publicado em 2014

Passive Immunization Reduces Behavioral and Neuropathological Deficits in an Alpha-Synuclein Transgenic Model of Lewy Body Disease

Por Masliah, Eliezer, Rockenstein, Edward, Mante, Michael, Crews, Leslie, Spencer, Brian, Adame, Anthony, Patrick, Christina, Trejo, Margarita, Ubhi, Kiren, Rohn, Troy T., Mueller-Steiner, Sarah, Seubert, Peter, Barbour, Robin, McConlogue, Lisa, Buttini, Manuel, Games, Dora, Schenk, Dale
Publicado em 2011

Epitope and isotype specificities of antibodies to β-amyloid peptide for protection against Alzheimer's disease-like neuropathology

Por Bard, Frédérique, Barbour, Robin, Cannon, Catherine, Carretto, Robert, Fox, Michael, Games, Dora, Guido, Teresa, Hoenow, Kathleen, Hu, Kang, Johnson-Wood, Kelly, Khan, Karen, Kholodenko, Dora, Lee, Celeste, Lee, Mike, Motter, Ruth, Nguyen, Minh, Reed, Amanda, Schenk, Dale, Tang, Pearl, Vasquez, Nicki, Seubert, Peter, Yednock, Ted
Publicado em 2003