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Dentate gyrus volume is reduced before onset of plaque formation in PDAPP mice: A magnetic resonance microscopy and stereologic analysis

High-resolution magnetic resonance microscopy (MRM) was used to determine regional brain volumetric changes in a mouse model of Alzheimer's disease. These transgenic (Tg) mice overexpress human mutant amyloid precursor protein (APP) V717F under control of platelet-derived growth factor promoter...

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Auteurs principaux: Redwine, Jeffrey M., Kosofsky, Barry, Jacobs, Russell E., Games, Dora, Reilly, John F., Morrison, John H., Young, Warren G., Bloom, Floyd E.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC298781/
https://ncbi.nlm.nih.gov/pubmed/12552120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.242746599
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