Morphological Characterization of Thioflavin-S-Positive Amyloid Plaques in Transgenic Alzheimer Mice and Effect of Passive Aβ Immunotherapy on Their Clearance

Transgenic mice mimicking certain features of Alzheimer’s disease (AD)-pathology, namely amyloid plaques and neurofibrillary tangles, have been developed in an effort to better understand the mechanism leading to the formation of these characteristic cerebral lesions. More recently, these animal mod...

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Main Authors: Bussière, Thierry, Bard, Frédérique, Barbour, Robin, Grajeda, Henry, Guido, Terry, Khan, Karen, Schenk, Dale, Games, Dora, Seubert, Peter, Buttini, Manuel
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2004
Teme:
Animal Model
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618604/
https://ncbi.nlm.nih.gov/pubmed/15331422
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