β-Amyloid Immunotherapy Prevents Synaptic Degeneration in a Mouse Model of Alzheimer's Disease

Alzheimer's disease neuropathology is characterized by key features that include the deposition of the amyloid β peptide (Aβ) into plaques, the formation of neurofibrillary tangles, and the loss of neurons and synapses in specific brain regions. The loss of synapses, and particularly the associ...

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Vydáno v:J Neurosci
Hlavní autoři: Buttini, Manuel, Masliah, Eliezer, Barbour, Robin, Grajeda, Henry, Motter, Ruth, Johnson-Wood, Kelly, Khan, Karen, Seubert, Peter, Freedman, Stephen, Schenk, Dale, Games, Dora
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2005
Témata:
Neurobiology of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725749/
https://ncbi.nlm.nih.gov/pubmed/16207868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1697-05.2005
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