Comparison of Neurodegenerative Pathology in Transgenic Mice Overexpressing V717F β-Amyloid Precursor Protein and Alzheimer’s Disease

Overexpression of mutated human amyloid precursor protein (hAPP717V→F) under control of platelet-derived growth factor promoter (PDAPP minigene) in transgenic (tg) mice results in neurodegenerative changes similar to Alzheimer’s disease (AD). To clarify the pathology of these mice, we studied images...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Masliah, Eliezer, Sisk, Abbyann, Mallory, Margaret, Mucke, Lennart, Schenk, Dale, Games, Dora
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1996
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6578961/
https://ncbi.nlm.nih.gov/pubmed/8795633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-18-05795.1996
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