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Fyn Kinase Modulates Synaptotoxicity, But Not Aberrant Sprouting, in Human Amyloid Precursor Protein Transgenic Mice

Alzheimer's disease (AD), the most common neurodegenerative disorder, results in progressive degeneration of synapses and aberrant sprouting of axon terminals. The mechanisms underlying these seemingly opposing cellular phenomena are unclear. We hypothesized that Fyn kinase may play a role in o...

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Detaylı Bibliyografya
Yayımlandı:J Neurosci
Asıl Yazarlar: Chin, Jeannie, Palop, Jorge J., Yu, Gui-Qiu, Kojima, Nobuhiko, Masliah, Eliezer, Mucke, Lennart
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2004
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729387/
https://ncbi.nlm.nih.gov/pubmed/15140940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0277-04.2004
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