Astroglial Expression of Human α(1)-Antichymotrypsin Enhances Alzheimer-like Pathology in Amyloid Protein Precursor Transgenic Mice

Proteases and their inhibitors play key roles in physiological and pathological processes. Cerebral amyloid plaques are a pathological hallmark of Alzheimer’s disease (AD). They contain amyloid-β (Aβ) peptides in tight association with the serine protease inhibitor α(1)-antichymotrypsin. 1,2 However...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Mucke, Lennart, Yu, Gui-Qiu, McConlogue, Lisa, Rockenstein, Edward M., Abraham, Carmela R., Masliah, Eliezer
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2000
Assuntos:
Regular Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885780/
https://ncbi.nlm.nih.gov/pubmed/11106573
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares