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Astroglial Expression of Human α(1)-Antichymotrypsin Enhances Alzheimer-like Pathology in Amyloid Protein Precursor Transgenic Mice
Proteases and their inhibitors play key roles in physiological and pathological processes. Cerebral amyloid plaques are a pathological hallmark of Alzheimer’s disease (AD). They contain amyloid-β (Aβ) peptides in tight association with the serine protease inhibitor α(1)-antichymotrypsin. 1,2 However...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Investigative Pathology
2000
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885780/ https://ncbi.nlm.nih.gov/pubmed/11106573 |
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