Aβ Deposition Is Associated with Neuropil Changes, but not with Overt Neuronal Loss in the Human Amyloid Precursor Protein V717F (PDAPP) Transgenic Mouse

The PDAPP transgenic mouse overexpresses human amyloid precursor protein V717F (PDAPP minigene) and develops age-related cerebral amyloid-β protein (Aβ) deposits similar to senile plaques in Alzheimer’s disease. We find age-related cortical and limbic Aβ deposition that begins at 8 months and progre...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Irizarry, Michael C., Soriano, Ferdie, McNamara, Megan, Page, Keith J., Schenk, Dale, Games, Dora, Hyman, Bradley T.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1997
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573263/
https://ncbi.nlm.nih.gov/pubmed/9278541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-18-07053.1997
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados