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Active β-Amyloid Immunization Restores Spatial Learning in PDAPP Mice Displaying Very Low Levels of β-Amyloid
The behavioral and biochemical impact of active immunization against human β-amyloid (Aβ) was assessed using male transgenic (Tg) mice overexpressing a human mutant amyloid precursor protein (heterozygous PDAPP mice) and littermate controls. Administration of aggregated Aβ(42) occurred at monthly in...
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| Publicado en: | J Neurosci |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Society for Neuroscience
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6672499/ https://ncbi.nlm.nih.gov/pubmed/17344403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3710-06.2007 |
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