Morphological Characterization of Thioflavin-S-Positive Amyloid Plaques in Transgenic Alzheimer Mice and Effect of Passive Aβ Immunotherapy on Their Clearance

Transgenic mice mimicking certain features of Alzheimer’s disease (AD)-pathology, namely amyloid plaques and neurofibrillary tangles, have been developed in an effort to better understand the mechanism leading to the formation of these characteristic cerebral lesions. More recently, these animal mod...

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Bibliographic Details
Main Authors: Bussière, Thierry, Bard, Frédérique, Barbour, Robin, Grajeda, Henry, Guido, Terry, Khan, Karen, Schenk, Dale, Games, Dora, Seubert, Peter, Buttini, Manuel
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2004
Subjects:
Animal Model
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618604/
https://ncbi.nlm.nih.gov/pubmed/15331422
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