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Defining the Conformational Features of Anchorless, Poorly Neuroinvasive Prions
Infectious prions cause diverse clinical signs and form an extraordinary range of structures, from amorphous aggregates to fibrils. How the conformation of a prion dictates the disease phenotype remains unclear. Mice expressing GPI-anchorless or GPI-anchored prion protein exposed to the same infecti...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3630170/ https://ncbi.nlm.nih.gov/pubmed/23637596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003280 |
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