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Enhanced neuroinvasion by smaller, soluble prions

Infectious prion aggregates can propagate from extraneural sites into the brain with remarkable efficiency, likely transported via peripheral nerves. Yet not all prions spread into the brain, and the physical properties of a prion that is capable of transit within neurons remain unclear. We hypothes...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Bett, Cyrus, Lawrence, Jessica, Kurt, Timothy D., Orru, Christina, Aguilar-Calvo, Patricia, Kincaid, Anthony E., Surewicz, Witold K., Caughey, Byron, Wu, Chengbiao, Sigurdson, Christina J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399838/
https://ncbi.nlm.nih.gov/pubmed/28431576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0430-z
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