Enhanced neuroinvasion by smaller, soluble prions

Infectious prion aggregates can propagate from extraneural sites into the brain with remarkable efficiency, likely transported via peripheral nerves. Yet not all prions spread into the brain, and the physical properties of a prion that is capable of transit within neurons remain unclear. We hypothes...

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Bibliographic Details
Published in:	Acta Neuropathol Commun
Main Authors:	Bett, Cyrus, Lawrence, Jessica, Kurt, Timothy D., Orru, Christina, Aguilar-Calvo, Patricia, Kincaid, Anthony E., Surewicz, Witold K., Caughey, Byron, Wu, Chengbiao, Sigurdson, Christina J.
Format:	Artigo
Language:	Inglês
Published:	BioMed Central 2017
Subjects:	Research
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5399838/ https://ncbi.nlm.nih.gov/pubmed/28431576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0430-z
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Enhanced neuroinvasion by smaller, soluble prions

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