Enhanced neuroinvasion by smaller, soluble prions

Infectious prion aggregates can propagate from extraneural sites into the brain with remarkable efficiency, likely transported via peripheral nerves. Yet not all prions spread into the brain, and the physical properties of a prion that is capable of transit within neurons remain unclear. We hypothes...

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Bibliografiska uppgifter
I publikationen:Acta Neuropathol Commun
Huvudupphovsmän: Bett, Cyrus, Lawrence, Jessica, Kurt, Timothy D., Orru, Christina, Aguilar-Calvo, Patricia, Kincaid, Anthony E., Surewicz, Witold K., Caughey, Byron, Wu, Chengbiao, Sigurdson, Christina J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2017
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399838/
https://ncbi.nlm.nih.gov/pubmed/28431576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0430-z
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