Llwytho...

Prion infection promotes extensive accumulation of α-synuclein in aged human α-synuclein transgenic mice

In neurodegenerative disorders of the aging population, misfolded proteins, such as PrP(Sc), α-synuclein, amyloid β protein and tau, can interact resulting in enhanced aggregation, cross seeding and accelerated disease progression. Previous reports have shown that in Creutzfeldt-Jakob disease and sc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Masliah, Eliezer, Rockenstein, Edward, Inglis, Chandra, Adame, Anthony, Bett, Cyrus, Lucero, Melanie, Sigurdson, Christina J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366356/
https://ncbi.nlm.nih.gov/pubmed/22460692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.19806
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