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Alpha-synuclein deficient mice are resistant to toxin-induced multiple system atrophy

Multiple systems atrophy (MSA) is a neurodegenerative disorder characterized by oligodendrocytic accumulations of alpha-synuclein (αsyn). Oxidative stress is a key mechanism proposed to underlie MSA pathology. To address the role of αsyn modifications, over and above general oxidative modifications,...

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Autori principali: Ubhi, Kiren, Rockenstein, Edward, Mante, Michael, Inglis, Chandra, Adame, Anthony, Patrick, Christina, Masliah, Eliezer
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049936/
https://ncbi.nlm.nih.gov/pubmed/20224454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0b013e328338ba6b
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