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Mitochondrial Inhibitor 3-Nitroproprionic Acid Enhances Oxidative Modification of Alpha-synuclein in a Transgenic Mouse Model of Multiple System Atrophy
Multiple system atrophy (MSA) is a progressive neurodegenerative disease characterized by autonomic failure, parkinsonism, cerebellar ataxia, and oligodendrocytic accumulation of alpha-synuclein (αsyn). Oxidative stress has been linked to neuronal death in MSA and the mitochondrial toxin 3-nitroprop...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885901/ https://ncbi.nlm.nih.gov/pubmed/19405128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22089 |
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