Lovastatin ameliorates α-synuclein accumulation and oxidation in transgenic mouse models of α-synucleinopathies

Alpha-synuclein (α-syn) aggregation is a neuropathological hallmark of many diseases including Dementia with Lewy Bodies (DLB) and Parkinson’s Disease (PD), collectively termed the α-synucleinopathies. The mechanisms underlying α-syn aggregation remain elusive though emerging science has hypothesize...

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Autores principales: Koob, Andrew O., Ubhi, Kiren, Paulsson, Johan F., Kelly, Jeffery, Rockenstein, Edward, Mante, Michael, Adame, Anthony, Masliah, Eliezer
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812599/
https://ncbi.nlm.nih.gov/pubmed/19944097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2009.11.015
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