The Effects of IRE1, ATF6, and PERK Signaling on adRP-Linked Rhodopsins

Por Chiang, Wei-Chieh Jerry, Lin, Jonathan H.
Publicado no Adv Exp Med Biol (2014)

IRE1 directs proteasomal and lysosomal degradation of misfolded rhodopsin

Por Chiang, Wei-Chieh, Messah, Carissa, Lin, Jonathan H.
Publicado em 2012

Endoplasmic Reticulum-Associated Degradation (ERAD) of Misfolded Glycoproteins and Mutant P23H Rhodopsin in Photoreceptor Cells

Por Kroeger, Heike, Chiang, Wei-Chieh, Lin, Jonathan H.
Publicado em 2012

Pathomechanisms of ATF6-Associated Cone Photoreceptor Diseases

Por Chiang, Wei-Chieh Jerry, Kroeger, Heike, Chea, Lulu, Lin, Jonathan H.
Publicado no Adv Exp Med Biol (2019)

Selective Activation of ATF6 and PERK Endoplasmic Reticulum Stress Signaling Pathways Prevent Mutant Rhodopsin Accumulation

Por Chiang, Wei-Chieh, Hiramatsu, Nobuhiko, Messah, Carissa, Kroeger, Heike, Lin, Jonathan H.
Publicado em 2012

Endoplasmic Reticulum Stress in Human Photoreceptor Diseases

Por Chan, Priscilla, Stolz, Julia, Kohl, Susanne, Chiang, Wei-Chieh, Lin, Jonathan H.
Publicado no Brain Res (2016)

ER stress and unfolded protein response in ocular health and disease

Por Kroeger, Heike, Chiang, Wei-Chieh, Felden, Julia, Nguyen, Amanda, Lin, Jonathan H.
Publicado no FEBS J (2018)

Multiple Mechanisms of Unfolded Protein Response–Induced Cell Death

Por Hiramatsu, Nobuhiko, Chiang, Wei-Chieh, Kurt, Timothy D., Sigurdson, Christina J., Lin, Jonathan H.
Publicado no Am J Pathol (2015)

Ablation of Chop Transiently Enhances Photoreceptor Survival but Does Not Prevent Retinal Degeneration in Transgenic Mice Expressing Human P23H Rhodopsin

Por Chiang, Wei-Chieh, Joseph, Victory, Yasumura, Douglas, Matthes, Michael T., Lewin, Alfred S., Gorbatyuk, Marina S., Ahern, Kelly, LaVail, Matthew M., Lin, Jonathan H.
Publicado no Adv Exp Med Biol (2016)

In Vivo Visualization of Endoplasmic Reticulum Stress in the Retina Using the ERAI Reporter Mouse

Por Alavi, Marcel V., Chiang, Wei-Chieh, Kroeger, Heike, Yasumura, Douglas, Matthes, Michael T., Iwawaki, Takao, LaVail, Matthew M., Gould, Douglas B., Lin, Jonathan H.
Publicado no Invest Ophthalmol Vis Sci (2015)

Robust Endoplasmic Reticulum-Associated Degradation of Rhodopsin Precedes Retinal Degeneration

Por Chiang, Wei-Chieh, Kroeger, Heike, Sakami, Sanae, Messah, Carissa, Yasumura, Douglas, Matthes, Michael T., Coppinger, Judith A., Palczewski, Krzysztof, LaVail, Matthew M., Lin, Jonathan H.
Publicado no Mol Neurobiol (2014)

Induction of Endoplasmic Reticulum Stress Genes, BiP and Chop, in Genetic and Environmental Models of Retinal Degeneration

Por Kroeger, Heike, Messah, Carissa, Ahern, Kelly, Gee, Jason, Joseph, Victory, Matthes, Michael T., Yasumura, Douglas, Gorbatyuk, Marina S., Chiang, Wei-Chieh, LaVail, Matthew M., Lin, Jonathan H.
Publicado em 2012

De Novo Prion Aggregates Trigger Autophagy in Skeletal Muscle

Por Joshi-Barr, Shivanjali, Bett, Cyrus, Chiang, Wei-Chieh, Trejo, Margarita, Goebel, Hans H., Sikorska, Beata, Liberski, Pawel, Raeber, Alex, Lin, Jonathan H., Masliah, Eliezer, Sigurdson, Christina J.
Publicado em 2014

Achromatopsia mutations target sequential steps of ATF6 activation

Por Chiang, Wei-Chieh, Chan, Priscilla, Wissinger, Bernd, Vincent, Ajoy, Skorczyk-Werner, Anna, Krawczyński, Maciej R., Kaufman, Randal J., Tsang, Stephen H., Héon, Elise, Kohl, Susanne, Lin, Jonathan H.
Publicado no Proc Natl Acad Sci U S A (2017)

The unfolded protein response regulator ATF6 promotes mesodermal differentiation

Por Kroeger, Heike, Grimsey, Neil, Paxman, Ryan, Chiang, Wei-Chieh, Plate, Lars, Jones, Ying, Shaw, Peter X., Trejo, JoAnn, Tsang, Stephen H., Powers, Evan, Kelly, Jeffery W., Wiseman, R. Luke, Lin, Jonathan H.
Publicado no Sci Signal (2018)

Autosomal recessive cone-rod dystrophy can be caused by mutations in the ATF6 gene

Por Skorczyk-Werner, Anna, Chiang, Wei-Chieh, Wawrocka, Anna, Wicher, Katarzyna, Jarmuż-Szymczak, Małgorzata, Kostrzewska-Poczekaj, Magdalena, Jamsheer, Aleksander, Płoski, Rafał, Rydzanicz, Małgorzata, Pojda-Wilczek, Dorota, Weisschuh, Nicole, Wissinger, Bernd, Kohl, Susanne, Lin, Jonathan H, Krawczyński, Maciej R
Publicado no Eur J Hum Genet (2017)

Multiexon deletion alleles of ATF6 linked to achromatopsia

Por Lee, Eun-Jin, Chiang, Wei-Chieh Jerry, Kroeger, Heike, Bi, Chloe Xiaoke, Chao, Daniel L., Skowronska-Krawczyk, Dorota, Mastey, Rebecca R., Tsang, Stephen H., Chea, Leon, Kim, Kyle, Lambert, Scott R., Grandjean, Julia M.D., Baumann, Britta, Audo, Isabelle, Kohl, Susanne, Moore, Anthony T., Wiseman, R. Luke, Carroll, Joseph, Lin, Jonathan H.
Publicado no JCI Insight (2020)

A 45 nm Stacked CMOS Image Sensor Process Technology for Submicron Pixel †

Por Takahashi, Seiji, Huang, Yi-Min, Sze, Jhy-Jyi, Wu, Tung-Ting, Guo, Fu-Sheng, Hsu, Wei-Cheng, Tseng, Tung-Hsiung, Liao, King, Kuo, Chin-Chia, Chen, Tzu-Hsiang, Chiang, Wei-Chieh, Chuang, Chun-Hao, Chou, Keng-Yu, Chung, Chi-Hsien, Chou, Kuo-Yu, Tseng, Chien-Hsien, Wang, Chuan-Joung, Yaung, Dun-Nien
Publicado no Sensors (Basel) (2017)

Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia

Por Kohl, Susanne, Zobor, Ditta, Chiang, Wei-Chieh, Weisschuh, Nicole, Staller, Jennifer, Menendez, Irene Gonzalez, Chang, Stanley, Beck, Susanne C, Garrido, Marina Garcia, Sothilingam, Vithiyanjali, Seeliger, Mathias W, Stanzial, Franco, Benedicenti, Francesco, Inzana, Francesca, Héon, Elise, Vincent, Ajoy, Beis, Jill, Strom, Tim M, Rudolph, Günther, Roosing, Susanne, den Hollander, Anneke I, Cremers, Frans P M, Lopez, Irma, Ren, Huanan, Moore, Anthony T, Webster, Andrew R, Michaelides, Michel, Koenekoop, Robert K, Zrenner, Eberhart, Kaufman, Randal J, Tsang, Stephen H, Wissinger, Bernd, Lin, Jonathan H
Publicado no Nat Genet (2015)