Ablation of Chop Transiently Enhances Photoreceptor Survival but Does Not Prevent Retinal Degeneration in Transgenic Mice Expressing Human P23H Rhodopsin

RHO (Rod opsin) encodes a G-protein coupled receptor that is expressed exclusively by rod photoreceptors of the retina and forms the essential photopigment, rhodopsin, when coupled with 11-cis-retinal. Many rod opsin disease mutations cause rod opsin protein misfolding and trigger endoplasmic reticu...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Adv Exp Med Biol
Hoofdauteurs: Chiang, Wei-Chieh, Joseph, Victory, Yasumura, Douglas, Matthes, Michael T., Lewin, Alfred S., Gorbatyuk, Marina S., Ahern, Kelly, LaVail, Matthew M., Lin, Jonathan H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731204/
https://ncbi.nlm.nih.gov/pubmed/26427410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-17121-0_25
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items