Robust Endoplasmic Reticulum-Associated Degradation of Rhodopsin Precedes Retinal Degeneration

Rhodopsin is a G protein-coupled receptor essential for vision and rod photoreceptor viability. Disease-associated rhodopsin mutations, such as P23H rhodopsin, cause rhodopsin protein misfolding and trigger endoplasmic reticulum (ER) stress, activating the Unfolded Protein Response (UPR). The pathop...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Neurobiol
मुख्य लेखकों: Chiang, Wei-Chieh, Kroeger, Heike, Sakami, Sanae, Messah, Carissa, Yasumura, Douglas, Matthes, Michael T., Coppinger, Judith A., Palczewski, Krzysztof, LaVail, Matthew M., Lin, Jonathan H.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383737/
https://ncbi.nlm.nih.gov/pubmed/25270370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-014-8881-8
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन