In Vivo Visualization of Endoplasmic Reticulum Stress in the Retina Using the ERAI Reporter Mouse

PURPOSE: Endoplasmic reticulum (ER) stress activates inositol requiring enzyme 1 (IRE1), a key regulator of the unfolded protein response. The ER stress activated indicator (ERAI) transgenic mouse expresses a yellow fluorescent GFP variant (Venus) when IRE1 is activated by ER stress. We tested wheth...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Invest Ophthalmol Vis Sci
Huvudupphovsmän: Alavi, Marcel V., Chiang, Wei-Chieh, Kroeger, Heike, Yasumura, Douglas, Matthes, Michael T., Iwawaki, Takao, LaVail, Matthew M., Gould, Douglas B., Lin, Jonathan H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Association for Research in Vision and Ophthalmology 2015
Ämnen:
Retinal Cell Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627472/
https://ncbi.nlm.nih.gov/pubmed/26513501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-16969
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk