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Pathomechanisms of ATF6-Associated Cone Photoreceptor Diseases
Activating transcription factor 6 (ATF6) is a key regulator of the unfolded protein response (UPR). In response to endoplasmic reticulum (ER) stress, ATF6 is transported from the ER to the Golgi apparatus where it is cleaved by intramembrane proteolysis, releasing its cytosolic fragment. The cleaved...
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| Publicado no: | Adv Exp Med Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7643264/ https://ncbi.nlm.nih.gov/pubmed/31884629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-030-27378-1_50 |
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