The unfolded protein response regulator ATF6 promotes mesodermal differentiation

ATF6 encodes a transcription factor that is anchored in the endoplasmic reticulum (ER) and activated during the unfolded protein response (UPR) to protect cells from ER stress. Deletion of the isoform activating transcription factor 6α (ATF6α) and its paralog ATF6β results in embryonic lethality and...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Kroeger, Heike, Grimsey, Neil, Paxman, Ryan, Chiang, Wei-Chieh, Plate, Lars, Jones, Ying, Shaw, Peter X., Trejo, JoAnn, Tsang, Stephen H., Powers, Evan, Kelly, Jeffery W., Wiseman, R. Luke, Lin, Jonathan H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957084/
https://ncbi.nlm.nih.gov/pubmed/29440509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aan5785
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