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Regulating Secretory Proteostasis Through the Unfolded Protein Response: From Function to Therapy
Imbalances in secretory proteostasis induced by genetic, environmental or aging related insults are pathologically associated with etiologically diverse protein misfolding diseases. To protect the secretory proteome from these insults, organisms evolved stress-responsive signaling pathways that regu...
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| Udgivet i: | Trends Cell Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5612838/ https://ncbi.nlm.nih.gov/pubmed/28647092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2017.05.006 |
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