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Regulating Secretory Proteostasis Through the Unfolded Protein Response: From Function to Therapy
Imbalances in secretory proteostasis induced by genetic, environmental or aging related insults are pathologically associated with etiologically diverse protein misfolding diseases. To protect the secretory proteome from these insults, organisms evolved stress-responsive signaling pathways that regu...
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| Publicado no: | Trends Cell Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5612838/ https://ncbi.nlm.nih.gov/pubmed/28647092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2017.05.006 |
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