Pluripotent stem cells reveal the developmental biology of human megakaryocytes and provide a source of platelets for clinical application

Por Takayama, Naoya, Eto, Koji
Publicado em 2012

Multicolor Staining of Globin Subtypes Reveals Impaired Globin Switching During Erythropoiesis in Human Pluripotent Stem Cells

Por Ochi, Kiyosumi, Takayama, Naoya, Hirose, Shoichi, Nakahata, Tatsutoshi, Nakauchi, Hiromitsu, Eto, Koji
Publicado em 2014

Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells

Por Kajiwara, Masatoshi, Aoi, Takashi, Okita, Keisuke, Takahashi, Ryosuke, Inoue, Haruhisa, Takayama, Naoya, Endo, Hiroshi, Eto, Koji, Toguchida, Junya, Uemoto, Shinji, Yamanaka, Shinya
Publicado em 2012

Reduction of N-Glycolylneuraminic Acid in Human Induced Pluripotent Stem Cells Generated or Cultured under Feeder- and Serum-Free Defined Conditions

Por Hayashi, Yohei, Chan, Techuan, Warashina, Masaki, Fukuda, Masakazu, Ariizumi, Takashi, Okabayashi, Koji, Takayama, Naoya, Otsu, Makoto, Eto, Koji, Furue, Miho Kusuda, Michiue, Tatsuo, Ohnuma, Kiyoshi, Nakauchi, Hiromitsu, Asashima, Makoto
Publicado em 2010

Congenital amegakaryocytic thrombocytopenia iPS cells exhibit defective MPL-mediated signaling

Por Hirata, Shinji, Takayama, Naoya, Jono-Ohnishi, Ryoko, Endo, Hiroshi, Nakamura, Sou, Dohda, Takeaki, Nishi, Masanori, Hamazaki, Yuhei, Ishii, Ei-ichi, Kaneko, Shin, Otsu, Makoto, Nakauchi, Hiromitsu, Kunishima, Shinji, Eto, Koji
Publicado em 2013

Profiling of MicroRNA in Human and Mouse ES and iPS Cells Reveals Overlapping but Distinct MicroRNA Expression Patterns

Por Razak, Siti Razila Abdul, Ueno, Kazuko, Takayama, Naoya, Nariai, Naoki, Nagasaki, Masao, Saito, Rika, Koso, Hideto, Lai, Chen-Yi, Murakami, Miyako, Tsuji, Koichiro, Michiue, Tatsuo, Nakauchi, Hiromitsu, Otsu, Makoto, Watanabe, Sumiko
Publicado em 2013

IL-1α induces thrombopoiesis through megakaryocyte rupture in response to acute platelet needs

Por Nishimura, Satoshi, Nagasaki, Mika, Kunishima, Shinji, Sawaguchi, Akira, Sakata, Asuka, Sakaguchi, Hiroyasu, Ohmori, Tsukasa, Manabe, Ichiro, Italiano, Joseph E., Ryu, Tomiko, Takayama, Naoya, Komuro, Issei, Kadowaki, Takashi, Eto, Koji, Nagai, Ryozo
Publicado no J Cell Biol (2015)

Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells

Por Takayama, Naoya, Nishimura, Satoshi, Nakamura, Sou, Shimizu, Takafumi, Ohnishi, Ryoko, Endo, Hiroshi, Yamaguchi, Tomoyuki, Otsu, Makoto, Nishimura, Ken, Nakanishi, Mahito, Sawaguchi, Akira, Nagai, Ryozo, Takahashi, Kazutoshi, Yamanaka, Shinya, Nakauchi, Hiromitsu, Eto, Koji
Publicado em 2010

Immortalization of Erythroblasts by c-MYC and BCL-XL Enables Large-Scale Erythrocyte Production from Human Pluripotent Stem Cells

Por Hirose, Sho-ichi, Takayama, Naoya, Nakamura, Sou, Nagasawa, Kazumichi, Ochi, Kiyosumi, Hirata, Shinji, Yamazaki, Satoshi, Yamaguchi, Tomoyuki, Otsu, Makoto, Sano, Shinya, Takahashi, Nobuyasu, Sawaguchi, Akira, Ito, Mamoru, Kato, Takashi, Nakauchi, Hiromitsu, Eto, Koji
Publicado em 2013

Lnk regulates integrin αIIbβ3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo

Por Takizawa, Hitoshi, Nishimura, Satoshi, Takayama, Naoya, Oda, Atsushi, Nishikii, Hidekazu, Morita, Yohei, Kakinuma, Sei, Yamazaki, Satoshi, Okamura, Satoshi, Tamura, Noriko, Goto, Shinya, Sawaguchi, Akira, Manabe, Ichiro, Takatsu, Kiyoshi, Nakauchi, Hiromitsu, Takaki, Satoshi, Eto, Koji
Publicado em 2009

DISTINCT ROUTES OF LINEAGE DEVELOPMENT RESHAPE THE HUMAN BLOOD HIERARCHY ACROSS ONTOGENY

Por Notta, Faiyaz, Zandi, Sasan, Takayama, Naoya, Dobson, Stephanie, Gan, Olga I, Wilson, Gavin, Kaufmann, Kerstin B, McLeod, Jessica, Laurenti, Elisa, Dunant, Cyrille F, McPherson, John D, Stein, Lincoln D, Dror, Yigal, Dick, John E
Publicado no Science (2015)

In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling

Por Nishimura, Satoshi, Manabe, Ichiro, Nagasaki, Mika, Kakuta, Shigeru, Iwakura, Yoichiro, Takayama, Naoya, Ooehara, Jun, Otsu, Makoto, Kamiya, Akihide, Petrich, Brian G., Urano, Tetsumei, Kadono, Takafumi, Sato, Shinichi, Aiba, Atsu, Yamashita, Hiroshi, Sugiura, Seiryo, Kadowaki, Takashi, Nakauchi, Hiromitsu, Eto, Koji, Nagai, Ryozo
Publicado em 2012

miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells

Por Lechman, Eric R., Gentner, Bernhard, Ng, Stanley W.K., Schoof, Erwin M., van Galen, Peter, Kennedy, James A., Nucera, Silvia, Ciceri, Fabio, Kaufmann, Kerstin B., Takayama, Naoya, Dobson, Stephanie M., Trotman-Grant, Aaron, Krivdova, Gabriela, Elzinga, Janneke, Mitchell, Amanda, Nilsson, Björn, Hermans, Karin G., Eppert, Kolja, Marke, Rene, Isserlin, Ruth, Voisin, Veronique, Bader, Gary D., Zandstra, Peter W., Golub, Todd R., Ebert, Benjamin L., Lu, Jun, Minden, Mark, Wang, Jean C.Y., Naldini, Luigi, Dick, John E.
Publicado no Cancer Cell (2016)

Mutant IDH1 downregulates ATM and alters DNA repair and sensitivity to DNA damage independent of TET2

Por Inoue, Satoshi, Li, Wanda Y., Tseng, Alan, Beerman, Isabel, Elia, Andrew J., Bendall, Sean C., Lemonnier, François, Kron, Ken J., Cescon, David W., Hao, Zhenyue, Lind, Evan F., Takayama, Naoya, Planello, Aline C., Shen, Shu Yi, Shih, Alan H., Larsen, Dana M., Li, Qinxi, Snow, Bryan E., Wakeham, Andrew, Haight, Jillian, Gorrini, Chiara, Bassi, Christian, Thu, Kelsie L., Murakami, Kiichi, Elford, Alisha R., Ueda, Takeshi, Straley, Kimberly, Yen, Katharine E., Melino, Gerry, Cimmino, Luisa, Aifantis, Iannis, Levine, Ross L., De Carvalho, Daniel D., Lupien, Mathieu, Rossi, Derrick J., Nolan, Garry P., Cairns, Rob A., Mak, Tak W.
Publicado no Cancer Cell (2016)