In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling

The mechanism by which thrombotic vessel occlusion occurs independently of plaque development or endothelial cell (EC) disruption remains unclear, largely because of an inability to visualize the formation of thrombus, especially at the single-platelet level in real time. Here we demonstrate that ra...

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Detalhes bibliográficos
Main Authors: Nishimura, Satoshi, Manabe, Ichiro, Nagasaki, Mika, Kakuta, Shigeru, Iwakura, Yoichiro, Takayama, Naoya, Ooehara, Jun, Otsu, Makoto, Kamiya, Akihide, Petrich, Brian G., Urano, Tetsumei, Kadono, Takafumi, Sato, Shinichi, Aiba, Atsu, Yamashita, Hiroshi, Sugiura, Seiryo, Kadowaki, Takashi, Nakauchi, Hiromitsu, Eto, Koji, Nagai, Ryozo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351094/
https://ncbi.nlm.nih.gov/pubmed/22096246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-09-381400
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