Lnk regulates integrin αIIbβ3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo

The nature of the in vivo cellular events underlying thrombus formation mediated by platelet activation remains unclear because of the absence of a modality for analysis. Lymphocyte adaptor protein (Lnk; also known as Sh2b3) is an adaptor protein that inhibits thrombopoietin-mediated signaling, and...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Takizawa, Hitoshi, Nishimura, Satoshi, Takayama, Naoya, Oda, Atsushi, Nishikii, Hidekazu, Morita, Yohei, Kakinuma, Sei, Yamazaki, Satoshi, Okamura, Satoshi, Tamura, Noriko, Goto, Shinya, Sawaguchi, Akira, Manabe, Ichiro, Takatsu, Kiyoshi, Nakauchi, Hiromitsu, Takaki, Satoshi, Eto, Koji
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Clinical Investigation 2009
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798683/
https://ncbi.nlm.nih.gov/pubmed/20038804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39503
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