Lnk regulates integrin αIIbβ3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo

The nature of the in vivo cellular events underlying thrombus formation mediated by platelet activation remains unclear because of the absence of a modality for analysis. Lymphocyte adaptor protein (Lnk; also known as Sh2b3) is an adaptor protein that inhibits thrombopoietin-mediated signaling, and...

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書誌詳細
主要な著者: Takizawa, Hitoshi, Nishimura, Satoshi, Takayama, Naoya, Oda, Atsushi, Nishikii, Hidekazu, Morita, Yohei, Kakinuma, Sei, Yamazaki, Satoshi, Okamura, Satoshi, Tamura, Noriko, Goto, Shinya, Sawaguchi, Akira, Manabe, Ichiro, Takatsu, Kiyoshi, Nakauchi, Hiromitsu, Takaki, Satoshi, Eto, Koji
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2009
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798683/
https://ncbi.nlm.nih.gov/pubmed/20038804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39503
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