Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction

One of the central tasks of stem cell biology is to understand the molecular mechanisms that control self-renewal in stem cells. Several cytokines are implicated as crucial regulators of hematopoietic stem cells (HSCs), but little is known about intracellular signaling for HSC self-renewal. To addre...

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Bibliographic Details
Main Authors: Seita, Jun, Ema, Hideo, Ooehara, Jun, Yamazaki, Satoshi, Tadokoro, Yuko, Yamasaki, Akiko, Eto, Koji, Takaki, Satoshi, Takatsu, Kiyoshi, Nakauchi, Hiromitsu
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2007
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892983/
https://ncbi.nlm.nih.gov/pubmed/17284614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606238104
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