A Double-Switch Vector System Positively Regulates Transgene Expression by Endogenous microRNA Expression (miR-ON Vector)

por Amendola, Mario, Giustacchini, Alice, Gentner, Bernhard, Naldini, Luigi
Publicado 2013

Engineered tumor-infiltrating macrophages as gene delivery vehicles for interferon-α activates immunity and inhibits breast cancer progression

por Escobar, Giulia, Gentner, Bernhard, Naldini, Luigi, Mazzieri, Roberta
Publicado 2014

Regulated and Multiple miRNA and siRNA Delivery Into Primary Cells by a Lentiviral Platform

por Amendola, Mario, Passerini, Laura, Pucci, Ferdinando, Gentner, Bernhard, Bacchetta, Rosa, Naldini, Luigi
Publicado 2009

MicroRNA-124 Is a Subventricular Zone Neuronal Fate Determinant

por Åkerblom, Malin, Sachdeva, Rohit, Barde, Isabelle, Verp, Sonia, Gentner, Bernhard, Trono, Didier, Jakobsson, Johan
Publicado en J Neurosci (2012)

Gene therapy for mucopolysaccharidoses: in vivo and ex vivo approaches

por Fraldi, Alessandro, Serafini, Marta, Sorrentino, Nicolina Cristina, Gentner, Bernhard, Aiuti, Alessandro, Bernardo, Maria Ester
Publicado en Ital J Pediatr (2018)

Dynamic Activity of miR-125b and miR-93 during Murine Neural Stem Cell Differentiation In Vitro and in the Subventricular Zone Neurogenic Niche

por Lattanzi, Annalisa, Gentner, Bernhard, Corno, Daniela, Di Tomaso, Tiziano, Mestdagh, Pieter, Speleman, Frank, Naldini, Luigi, Gritti, Angela
Publicado 2013

Design of a regulated lentiviral vector for hematopoietic stem cell gene therapy of globoid cell leukodystrophy

por Ungari, Silvia, Montepeloso, Annita, Morena, Francesco, Cocchiarella, Fabienne, Recchia, Alessandra, Martino, Sabata, Gentner, Bernhard, Naldini, Luigi, Biffi, Alessandra
Publicado en Mol Ther Methods Clin Dev (2015)

Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors

por Sachdeva, Rohit, Jönsson, Marie E., Nelander, Jenny, Kirkeby, Agnete, Guibentif, Carolina, Gentner, Bernhard, Naldini, Luigi, Björklund, Anders, Parmar, Malin, Jakobsson, Johan
Publicado 2010

The galactocerebrosidase enzyme contributes to the maintenance of a functional hematopoietic stem cell niche

por Visigalli, Ilaria, Ungari, Silvia, Martino, Sabata, Park, Hyejung, Cesani, Martina, Gentner, Bernhard, Sergi Sergi, Lucia, Orlacchio, Aldo, Naldini, Luigi, Biffi, Alessandra
Publicado 2010

Efficient Ex Vivo Engineering and Expansion of Highly Purified Human Hematopoietic Stem and Progenitor Cell Populations for Gene Therapy

por Zonari, Erika, Desantis, Giacomo, Petrillo, Carolina, Boccalatte, Francesco E., Lidonnici, Maria Rosa, Kajaste-Rudnitski, Anna, Aiuti, Alessandro, Ferrari, Giuliana, Naldini, Luigi, Gentner, Bernhard
Publicado en Stem Cell Reports (2017)

Lentiviral vectors escape innate sensing but trigger p53 in human hematopoietic stem and progenitor cells

por Piras, Francesco, Riba, Michela, Petrillo, Carolina, Lazarevic, Dejan, Cuccovillo, Ivan, Bartolaccini, Sara, Stupka, Elia, Gentner, Bernhard, Cittaro, Davide, Naldini, Luigi, Kajaste‐Rudnitski, Anna
Publicado en EMBO Mol Med (2017)

Assessing the Impact of Cyclosporin A on Lentiviral Transduction and Preservation of Human Hematopoietic Stem Cells in Clinically Relevant Ex Vivo Gene Therapy Settings

por Petrillo, Carolina, Calabria, Andrea, Piras, Francesco, Capotondo, Alessia, Spinozzi, Giulio, Cuccovillo, Ivan, Benedicenti, Fabrizio, Naldini, Luigi, Montini, Eugenio, Biffi, Alessandra, Gentner, Bernhard, Kajaste-Rudnitski, Anna
Publicado en Hum Gene Ther (2019)

ATIM-36. TEM-GBM-001 STUDY: AUTOLOGOUS CD34+ ENRICHED HEMATOPOIETIC PROGENITOR CELLS GENETICALLY MODIFIED FOR HUMAN INTERFERON-α2 & ADMINISTERED TO PATIENTS WITH GLIOBLASTOMA & AN...

por Finocchiaro, Gaetano, Gentner, Bernhard, Ciceri, Fabio, DiMeco, Francesco, Legnani, Federico, Eoli, Marica, Pollo, Bianca, Farina, Francesca, Zambanini, Andrew, Mazzoleni, Stefania, Russo, Carlo, Naldini, Luigi
Publicado en Neuro Oncol (2019)

Lentiviral Vector Gene Therapy Protects XCGD Mice From Acute Staphylococcus aureus Pneumonia and Inflammatory Response

por Farinelli, Giada, Jofra Hernandez, Raisa, Rossi, Alice, Ranucci, Serena, Sanvito, Francesca, Migliavacca, Maddalena, Brombin, Chiara, Pramov, Aleksandar, Di Serio, Clelia, Bovolenta, Chiara, Gentner, Bernhard, Bragonzi, Alessandra, Aiuti, Alessandro
Publicado en Mol Ther (2016)

MicroRNA-127-3p controls murine hematopoietic stem cell maintenance by limiting differentiation

por Crisafulli, Laura, Muggeo, Sharon, Uva, Paolo, Wang, Yulei, Iwasaki, Masayuki, Locatelli, Silvia, Anselmo, Achille, Colombo, Federico S., Carlo-Stella, Carmelo, Cleary, Michael L., Villa, Anna, Gentner, Bernhard, Ficara, Francesca
Publicado en Haematologica (2019)

Interferon gene therapy reprograms the leukemia microenvironment inducing protective immunity to multiple tumor antigens

por Escobar, Giulia, Barbarossa, Luigi, Barbiera, Giulia, Norelli, Margherita, Genua, Marco, Ranghetti, Anna, Plati, Tiziana, Camisa, Barbara, Brombin, Chiara, Cittaro, Davide, Annoni, Andrea, Bondanza, Attilio, Ostuni, Renato, Gentner, Bernhard, Naldini, Luigi
Publicado en Nat Commun (2018)

Attenuation of miR-126 Activity Expands HSC In Vivo without Exhaustion

por Lechman, Eric R., Gentner, Bernhard, van Galen, Peter, Giustacchini, Alice, Saini, Massimo, Boccalatte, Francesco E., Hiramatsu, Hidefumi, Restuccia, Umberto, Bachi, Angela, Voisin, Veronique, Bader, Gary D., Dick, John E., Naldini, Luigi
Publicado 2012

Targeting a Pre-existing Anti-transgene T Cell Response for Effective Gene Therapy of MPS-I in the Mouse Model of the Disease

por Squeri, Giorgia, Passerini, Laura, Ferro, Francesca, Laudisa, Cecilia, Tomasoni, Daniela, Deodato, Federica, Donati, Maria Alice, Gasperini, Serena, Aiuti, Alessandro, Bernardo, Maria Ester, Gentner, Bernhard, Naldini, Luigi, Annoni, Andrea, Biffi, Alessandra, Gregori, Silvia
Publicado en Mol Ther (2019)

Plerixafor and G-CSF combination mobilizes hematopoietic stem and progenitors cells with a distinct transcriptional profile and a reduced in vivo homing capacity compared to plerix...

por Lidonnici, Maria Rosa, Aprile, Annamaria, Frittoli, Marta Claudia, Mandelli, Giacomo, Paleari, Ylenia, Spinelli, Antonello, Gentner, Bernhard, Zambelli, Matilde, Parisi, Cristina, Bellio, Laura, Cassinerio, Elena, Zanaboni, Laura, Cappellini, Maria Domenica, Ciceri, Fabio, Marktel, Sarah, Ferrari, Giuliana
Publicado en Haematologica (2017)

MicroRNA-126–mediated control of cell fate in B-cell myeloid progenitors as a potential alternative to transcriptional factors

por Okuyama, Kazuki, Ikawa, Tomokatsu, Gentner, Bernhard, Hozumi, Katsuto, Harnprasopwat, Ratanakanit, Lu, Jun, Yamashita, Riu, Ha, Daon, Toyoshima, Takae, Chanda, Bidisha, Kawamata, Toyotaka, Yokoyama, Kazuaki, Wang, Shusheng, Ando, Kiyoshi, Lodish, Harvey F., Tojo, Arinobu, Kawamoto, Hiroshi, Kotani, Ai
Publicado 2013