A Double-Switch Vector System Positively Regulates Transgene Expression by Endogenous microRNA Expression (miR-ON Vector)

Por Amendola, Mario, Giustacchini, Alice, Gentner, Bernhard, Naldini, Luigi
Publicado em 2013

Engineered tumor-infiltrating macrophages as gene delivery vehicles for interferon-α activates immunity and inhibits breast cancer progression

Por Escobar, Giulia, Gentner, Bernhard, Naldini, Luigi, Mazzieri, Roberta
Publicado em 2014

Regulated and Multiple miRNA and siRNA Delivery Into Primary Cells by a Lentiviral Platform

Por Amendola, Mario, Passerini, Laura, Pucci, Ferdinando, Gentner, Bernhard, Bacchetta, Rosa, Naldini, Luigi
Publicado em 2009

MicroRNA-124 Is a Subventricular Zone Neuronal Fate Determinant

Por Åkerblom, Malin, Sachdeva, Rohit, Barde, Isabelle, Verp, Sonia, Gentner, Bernhard, Trono, Didier, Jakobsson, Johan
Publicado no J Neurosci (2012)

Dynamic Activity of miR-125b and miR-93 during Murine Neural Stem Cell Differentiation In Vitro and in the Subventricular Zone Neurogenic Niche

Por Lattanzi, Annalisa, Gentner, Bernhard, Corno, Daniela, Di Tomaso, Tiziano, Mestdagh, Pieter, Speleman, Frank, Naldini, Luigi, Gritti, Angela
Publicado em 2013

Design of a regulated lentiviral vector for hematopoietic stem cell gene therapy of globoid cell leukodystrophy

Por Ungari, Silvia, Montepeloso, Annita, Morena, Francesco, Cocchiarella, Fabienne, Recchia, Alessandra, Martino, Sabata, Gentner, Bernhard, Naldini, Luigi, Biffi, Alessandra
Publicado no Mol Ther Methods Clin Dev (2015)

Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors

Por Sachdeva, Rohit, Jönsson, Marie E., Nelander, Jenny, Kirkeby, Agnete, Guibentif, Carolina, Gentner, Bernhard, Naldini, Luigi, Björklund, Anders, Parmar, Malin, Jakobsson, Johan
Publicado em 2010

The galactocerebrosidase enzyme contributes to the maintenance of a functional hematopoietic stem cell niche

Por Visigalli, Ilaria, Ungari, Silvia, Martino, Sabata, Park, Hyejung, Cesani, Martina, Gentner, Bernhard, Sergi Sergi, Lucia, Orlacchio, Aldo, Naldini, Luigi, Biffi, Alessandra
Publicado em 2010

Efficient Ex Vivo Engineering and Expansion of Highly Purified Human Hematopoietic Stem and Progenitor Cell Populations for Gene Therapy

Por Zonari, Erika, Desantis, Giacomo, Petrillo, Carolina, Boccalatte, Francesco E., Lidonnici, Maria Rosa, Kajaste-Rudnitski, Anna, Aiuti, Alessandro, Ferrari, Giuliana, Naldini, Luigi, Gentner, Bernhard
Publicado no Stem Cell Reports (2017)

Lentiviral Vector Gene Therapy Protects XCGD Mice From Acute Staphylococcus aureus Pneumonia and Inflammatory Response

Por Farinelli, Giada, Jofra Hernandez, Raisa, Rossi, Alice, Ranucci, Serena, Sanvito, Francesca, Migliavacca, Maddalena, Brombin, Chiara, Pramov, Aleksandar, Di Serio, Clelia, Bovolenta, Chiara, Gentner, Bernhard, Bragonzi, Alessandra, Aiuti, Alessandro
Publicado no Mol Ther (2016)

Attenuation of miR-126 Activity Expands HSC In Vivo without Exhaustion

Por Lechman, Eric R., Gentner, Bernhard, van Galen, Peter, Giustacchini, Alice, Saini, Massimo, Boccalatte, Francesco E., Hiramatsu, Hidefumi, Restuccia, Umberto, Bachi, Angela, Voisin, Veronique, Bader, Gary D., Dick, John E., Naldini, Luigi
Publicado em 2012

Plerixafor and G-CSF combination mobilizes hematopoietic stem and progenitors cells with a distinct transcriptional profile and a reduced in vivo homing capacity compared to plerix...

Por Lidonnici, Maria Rosa, Aprile, Annamaria, Frittoli, Marta Claudia, Mandelli, Giacomo, Paleari, Ylenia, Spinelli, Antonello, Gentner, Bernhard, Zambelli, Matilde, Parisi, Cristina, Bellio, Laura, Cassinerio, Elena, Zanaboni, Laura, Cappellini, Maria Domenica, Ciceri, Fabio, Marktel, Sarah, Ferrari, Giuliana
Publicado no Haematologica (2017)

MicroRNA-126–mediated control of cell fate in B-cell myeloid progenitors as a potential alternative to transcriptional factors

Por Okuyama, Kazuki, Ikawa, Tomokatsu, Gentner, Bernhard, Hozumi, Katsuto, Harnprasopwat, Ratanakanit, Lu, Jun, Yamashita, Riu, Ha, Daon, Toyoshima, Takae, Chanda, Bidisha, Kawamata, Toyotaka, Yokoyama, Kazuaki, Wang, Shusheng, Ando, Kiyoshi, Lodish, Harvey F., Tojo, Arinobu, Kawamoto, Hiroshi, Kotani, Ai
Publicado em 2013

Targeted Genome Editing in Human Repopulating Hematopoietic Stem Cells

Por Genovese, Pietro, Schiroli, Giulia, Escobar, Giulia, Tomaso, Tiziano Di, Firrito, Claudia, Calabria, Andrea, Moi, Davide, Mazzieri, Roberta, Bonini, Chiara, Holmes, Michael C., Gregory, Philip D., van der Burg, Mirjam, Gentner, Bernhard, Montini, Eugenio, Lombardo, Angelo, Naldini, Luigi
Publicado em 2014

Dual-regulated Lentiviral Vector for Gene Therapy of X-linked Chronic Granulomatosis

Por Chiriaco, Maria, Farinelli, Giada, Capo, Valentina, Zonari, Erika, Scaramuzza, Samantha, Di Matteo, Gigliola, Sergi, Lucia Sergi, Migliavacca, Maddalena, Hernandez, Raisa Jofra, Bombelli, Ferdinando, Giorda, Ezio, Kajaste-Rudnitski, Anna, Trono, Didier, Grez, Manuel, Rossi, Paolo, Finocchi, Andrea, Naldini, Luigi, Gentner, Bernhard, Aiuti, Alessandro
Publicado no Mol Ther (2014)

MicroRNA-223 dose levels fine tune proliferation and differentiation in human cord blood progenitors and acute myeloid leukemia

Por Gentner, Bernhard, Pochert, Nicole, Rouhi, Arefeh, Boccalatte, Francesco, Plati, Tiziana, Berg, Tobias, Sun, Su Ming, Mah, Sarah M., Mirkovic-Hösle, Milijana, Ruschmann, Jens, Muranyi, Andrew, Leierseder, Simon, Argiropoulos, Bob, Starczynowski, Daniel T., Karsan, Aly, Heuser, Michael, Hogge, Donna, Camargo, Fernando D., Engelhardt, Stefan, Döhner, Hartmut, Buske, Christian, Jongen-Lavrencic, Mojca, Naldini, Luigi, Humphries, R. Keith, Kuchenbauer, Florian
Publicado no Exp Hematol (2015)

miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells

Por Lechman, Eric R., Gentner, Bernhard, Ng, Stanley W.K., Schoof, Erwin M., van Galen, Peter, Kennedy, James A., Nucera, Silvia, Ciceri, Fabio, Kaufmann, Kerstin B., Takayama, Naoya, Dobson, Stephanie M., Trotman-Grant, Aaron, Krivdova, Gabriela, Elzinga, Janneke, Mitchell, Amanda, Nilsson, Björn, Hermans, Karin G., Eppert, Kolja, Marke, Rene, Isserlin, Ruth, Voisin, Veronique, Bader, Gary D., Zandstra, Peter W., Golub, Todd R., Ebert, Benjamin L., Lu, Jun, Minden, Mark, Wang, Jean C.Y., Naldini, Luigi, Dick, John E.
Publicado no Cancer Cell (2016)