Cyclosporin A and Rapamycin Relieve Distinct Lentiviral Restriction Blocks in Hematopoietic Stem and Progenitor Cells

Por Petrillo, Carolina, Cesana, Daniela, Piras, Francesco, Bartolaccini, Sara, Naldini, Luigi, Montini, Eugenio, Kajaste-Rudnitski, Anna
Publicado no Mol Ther (2015)

Efficient Ex Vivo Engineering and Expansion of Highly Purified Human Hematopoietic Stem and Progenitor Cell Populations for Gene Therapy

Por Zonari, Erika, Desantis, Giacomo, Petrillo, Carolina, Boccalatte, Francesco E., Lidonnici, Maria Rosa, Kajaste-Rudnitski, Anna, Aiuti, Alessandro, Ferrari, Giuliana, Naldini, Luigi, Gentner, Bernhard
Publicado no Stem Cell Reports (2017)

Lentiviral vectors escape innate sensing but trigger p53 in human hematopoietic stem and progenitor cells

Por Piras, Francesco, Riba, Michela, Petrillo, Carolina, Lazarevic, Dejan, Cuccovillo, Ivan, Bartolaccini, Sara, Stupka, Elia, Gentner, Bernhard, Cittaro, Davide, Naldini, Luigi, Kajaste‐Rudnitski, Anna
Publicado no EMBO Mol Med (2017)

Assessing the Impact of Cyclosporin A on Lentiviral Transduction and Preservation of Human Hematopoietic Stem Cells in Clinically Relevant Ex Vivo Gene Therapy Settings

Por Petrillo, Carolina, Calabria, Andrea, Piras, Francesco, Capotondo, Alessia, Spinozzi, Giulio, Cuccovillo, Ivan, Benedicenti, Fabrizio, Naldini, Luigi, Montini, Eugenio, Biffi, Alessandra, Gentner, Bernhard, Kajaste-Rudnitski, Anna
Publicado no Hum Gene Ther (2019)

Cyclosporine H Overcomes Innate Immune Restrictions to Improve Lentiviral Transduction and Gene Editing In Human Hematopoietic Stem Cells

Por Petrillo, Carolina, Thorne, Lucy G., Unali, Giulia, Schiroli, Giulia, Giordano, Anna M.S., Piras, Francesco, Cuccovillo, Ivan, Petit, Sarah J., Ahsan, Fatima, Noursadeghi, Mahdad, Clare, Simon, Genovese, Pietro, Gentner, Bernhard, Naldini, Luigi, Towers, Greg J., Kajaste-Rudnitski, Anna
Publicado no Cell Stem Cell (2018)