The galactocerebrosidase enzyme contributes to the maintenance of a functional hematopoietic stem cell niche

The balance between survival and death in many cell types is regulated by small changes in the intracellular content of bioactive sphingolipids. Enzymes that either produce or degrade these sphingolipids control this equilibrium. The findings here described indicate that the lysosomal galactocerebro...

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Bibliographic Details
Main Authors: Visigalli, Ilaria, Ungari, Silvia, Martino, Sabata, Park, Hyejung, Cesani, Martina, Gentner, Bernhard, Sergi Sergi, Lucia, Orlacchio, Aldo, Naldini, Luigi, Biffi, Alessandra
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2010
Subjects:
Hematopoiesis and Stem Cells
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173985/
https://ncbi.nlm.nih.gov/pubmed/20511539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-12-256461
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