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Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells

Hepatocytes generated from human induced pluripotent stem cells (hiPSCs) are unprecedented resources for pharmaceuticals and cell therapy. However, the in vitro directed differentiation of human pluripotent stem cells into mature hepatocytes remains challenging. Little attention has so far been paid...

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Detalhes bibliográficos
Main Authors: Kajiwara, Masatoshi, Aoi, Takashi, Okita, Keisuke, Takahashi, Ryosuke, Inoue, Haruhisa, Takayama, Naoya, Endo, Hiroshi, Eto, Koji, Toguchida, Junya, Uemoto, Shinji, Yamanaka, Shinya
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411998/
https://ncbi.nlm.nih.gov/pubmed/22802639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209979109
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