Загрузка...
Suppression of Indued Pluripotent Stem Cell Generation by the p53-p21 Pathway
Induced pluripotent stem (iPS) cells can be generated from somatic cells by introduction of Oct3/4, Sox2, Klf4 and c-Myc, in mouse1-4 and human5-8. Efficiency of this process, however, is low9. Pluripotency can be induced without c-Myc, but with even lower efficiency10,11. A p53 siRNA was recently s...
Сохранить в:
| Главные авторы: | , , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2917235/ https://ncbi.nlm.nih.gov/pubmed/19668191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08235 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|