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Generation and Characterization of Induced Pluripotent Stem Cells from Aid-Deficient Mice

It has been shown that DNA demethylation plays a pivotal role in the generation of induced pluripotent stem (iPS) cells. However, the underlying mechanism of this action is still unclear. Previous reports indicated that activation-induced cytidine deaminase (Aid, also known as Aicda) is involved in...

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Bibliografiske detaljer
Main Authors: Shimamoto, Ren, Amano, Naoki, Ichisaka, Tomoko, Watanabe, Akira, Yamanaka, Shinya, Okita, Keisuke
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981863/
https://ncbi.nlm.nih.gov/pubmed/24718089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094735
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